Author

Sophie Lotersztajn

InsermORCID 0000-0002-0053-7807Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Alain TedguiiD· 1 shared Anne FougeratiD· 1 shared Arnaud PolizziiD· 1 shared Benoît ChassaingiD· 1 shared Camille A. KnospiD· 1 shared Céline Marie Pauline Martin· 1 shared Charlène J. G. DauriatiD· 1 shared Charles CaëriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Alain TedguiORCID

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Author profile →

3 papers

Recent·Most cited

Mucosal-Associated Invariant T Cells Promote Atherosclerosis Through Monocyte-Driven Inflammation

Tobias Radecke, Thomas Nipoti, Louise Z Wang, Nirmala Mouttoulingam, Marc Diedisheim, Mouna Chajadine, Emilie Bacquer, Coraline Heron, Paul Alayrac, Charles Caër, Ludivine Laurans, Camille A. Knosp, Pierre Liénart, Kenza Damache, Rida Al-Rifai, , Soraya Taleb

This study identifies MAIT cells as contributors to atherosclerosis through monocyte-driven inflammation, showing their enrichment in plaques and protective effects when depleted.

bioRxiv · Jan 21, 2026 · PreprintImmunology

Effect of thermoneutral housing on MASLD severity, hepatic gene expression, and BAT activation during β3-adrenergic stimulation in mice

Céline Marie Pauline Martin, Arnaud Polizzi, Valérie Alquier‐Bacquie, Marine Huillet, Clémence Rives, Charlène J. G. Dauriat, Justine Bruse, Valentine Melin, Claire Naylies, Yannick Lippi, Frédéric Lasserre, JingHong Wan, Rémy Florès-Florès, Justine Bertrand‐Michel, Florence Blas-Y-Estrada, , Nicolas Loiseau

This study shows thermoneutral housing worsens MASLD in mice by increasing obesity, inflammation, fibrosis, and impairing BAT activation during β3-adrenergic stimulation.

iScience · Jul 26, 2025Peer-reviewedPhysiology

Fc immunoreceptors promote autophagy to regulate monocyte functions

Mathilde Nugue, Marie D’Allemagne, Despoina Koumantou, Mathias Vétillard, Mark Steven Cragg, Pierre Bourdely, Sophie Lotersztajn, Loredana Saveanu

This study shows that Fc receptors trigger autophagy, which modulates monocyte functions like cytokine production and phagocytosis.

bioRxiv · Aug 29, 2024 · PreprintCell Biology