Misbah Abbas

Primate Astrocyte Evolution Controls the Tempo of Neuronal Development

This study shows human astrocytes delay neuronal maturation compared to chimpanzee astrocytes, linking astrocyte evolution to brain neoteny and disease vulnerability.

Evolutionary diversification of lipid logistics shapes synaptic maturation in primates

This study compares human and chimpanzee neurons to show that human neurons have altered lipid metabolism and trafficking, contributing to delayed synaptic maturation during brain development.

Molecular signature of primate astrocytes reveals pathways and regulatory changes contributing to the human brain evolution

The paper identifies molecular changes in human astrocytes compared to non-human primates, revealing regulatory mechanisms linked to brain evolution.