Author

Jinfang Zhu

National Institutes of HealthORCID 0000-0002-0117-4745Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Danping WeiiD· 2 shared Keji ZhaoiD· 2 shared Xi CheniD· 2 shared Xiaoliang Zhu· 2 shared Yaqiang CaoiD· 2 shared Adrian Madrigal-AvilésiD· 1 shared Ahmed N. HegazyiD· 1 shared Anne Gégonne· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersImmunology

Danping WeiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The transcription factor Bhlhe40 promotes inflammatory functions of ILC2s through inducing GM-CSF while inhibiting IL-10 expression

Xiaoliang Zhu, Jian Song, Jia Nie, Xi Chen, Yaqiang Cao, Danping Wei, Rama Krishna Gurram, Dingkang Peng, Keji Zhao, Rémy Bosselut, Jinfang Zhu

This study shows Bhlhe40 promotes GM-CSF and inhibits IL-10 in ILC2s, enhancing eosinophil recruitment during type 2 immune responses.

bioRxiv · Aug 25, 2026 · PreprintImmunology

Stable characteristics of intrapopulation heterogeneity in virus-specific Th1 cells during chronic viral challenge infection

Valerie Plajer, Adrian Madrigal-Avilés, Maria R. Dzamukova, Nayar Durán-Hernández, Philippe Saikali, Vivien Holecska, Isabel Panse, Katrin Lehmann, Jinfang Zhu, Mir-Farzin Mashreghi, Ahmed N. Hegazy, Caroline Peine, Max Löhning

The paper examines T-bet expression stability in virus-specific Th1 cells during chronic infection, finding that quantitative differences persist and some cells retain Tfh-like features.

Frontiers in Immunology · Dec 19, 2025Peer-reviewedImmunology

Optimal CXCR5 Expression during Tfh Maturation Involves the Bhlhe40-Pou2af1 Axis

Xiaoliang Zhu, Xi Chen, Yaqiang Cao, Chengyu Liu, Zoey J. Kline, Gangqing Hu, Sundar Ganesan, Tibor Z. Veres, Difeng Fang, Shuai Liu, Danping Wei, Hirofumi Shibata, Dominic P. Golec, Hyunwoo Chung, Ronald N. Germain, , Jinfang Zhu

This study identifies the Bhlhe40-Pou2af1 axis as a transcriptional regulator of CXCR5 expression in Tfh cells, independent of the Bcl6-Blimp1 pathway.

Cell Reports · Oct 23, 2025Peer-reviewedImmunology

BRD4 expression in microglia supports recruitment of T cells into the CNS and exacerbates EAE

Anup Dey, Matthew J Butcher, Anne Gégonne, Dinah S. Singer, Jinfang Zhu, Keiko Ozato

This study shows that microglia-specific Brd4 knockout reduces T cell reactivation and EAE pathology by impairing microglia-T cell interactions and neuroinflammation.

bioRxiv · Sep 13, 2024 · PreprintNeuroscience