Author

Nathan Smits

The University of QueenslandORCID 0000-0002-0156-5076Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:long-read sequencing· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Geoffrey J. FaulkneriD· 3 shared Adam D. EwingiD· 2 shared Francisco Jose Sanchez-LuqueiD· 2 shared Jamila FaivreiD· 2 shared Patricia GerdesiD· 2 shared Sandra R. RichardsoniD· 2 shared Alberto Anastacio AmarillaiD· 1 shared Alexander A. KhromykhiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersGenomics

Geoffrey J. FaulknerORCID

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Author profile →

3 papers

Recent·Most cited

Revisiting the impact of synthetic ORF sequences on engineered LINE-1 retrotransposition

Dorothy Leung-Kwan Chan, Stephanie Workman, Nathan Smits, Alexander L. Carleton, Patricia Gerdes, Jeffrey S. Han, Jef D. Boeke, Geoffrey J. Faulkner, Sandra R. Richardson

This study shows that synthetic mouse L1 retrotransposition efficiency is due to sequence changes and a 3UTR deletion, not just ORF GC content, and highlights the need to reconsider synthetic L1 constructs.

bioRxiv · Aug 29, 2022 · PreprintMolecular Biology

No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing

Nathan Smits, Jay Rasmussen, Gabriela Oana Bodea, Alberto Anastacio Amarilla, Patricia Gerdes, Francisco Jose Sanchez-Luque, Prabha Ajjikuttira, Naphak Modhiran, Benjamin Liang, Jamila Faivre, Ira W. Deveson, Alexander A. Khromykh, Daniel Watterson, Adam D. Ewing, Geoffrey J. Faulkner

The paper uses long-read sequencing to investigate SARS-CoV-2 integration into the human genome and finds no evidence of such integration in infected cells.

Cell Reports · Jul 28, 2021Peer-reviewedGenomics

Nanopore sequencing enables comprehensive transposable element epigenomic profiling

Adam D. Ewing, Nathan Smits, Francisco Jose Sanchez-Luque, Jamila Faivre, Paul Martin Brennan, Sandra R. Richardson, Seth W. Cheetham, Geoffrey J. Faulkner

This study uses nanopore sequencing and the TLDR tool to profile CpG methylation of transposable elements in human tissues and tumors.

Molecular Cell · Nov 12, 2020Peer-reviewedGenomics