Mouse L1s fade with age: a methylation-enforced mechanism for attenuation of L1 retrotransposition potential
Patricia Gerdes, Dorothy Leung-Kwan Chan, Mischa Lundberg, Francisco Jose Sanchez-Luque, Gabriela Oana Bodea, Adam D. Ewing, Geoffrey J. Faulkner, Sandra R. Richardson
The paper investigates how L1 retrotransposition potential declines with age through methylation changes and promoter shortening in mice.
Genome Research · Sep 1, 2023Peer-reviewedGenetics