Author

Rashmi Kamble

Amsterdam University Medical Centers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1

Frequent Co-Authors

Riekelt H. HoutkooperiD· 3 shared Aldo JongejaniD· 2 shared Arwen W. GaoiD· 2 shared Georges E. JanssensiD· 2 shared Marte MolenaarsiD· 2 shared Rebecca L. McIntyreiD· 2 shared Alyson W. MacInnesiD· 1 shared Basten L. SnoekiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMolecular Biology

Riekelt H. HoutkooperORCID

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3 papers

Recent·Most cited

Inhibition of the neuromuscular acetylcholine receptor with atracurium activates FOXO/DAF-16-induced longevity

Rebecca L. McIntyre, Simone W. Denis, Rashmi Kamble, Marte Molenaars, Michael Angelo Petr, Bauke V. Schomakers, Mizanur Rahman, Siddhartha Datta Gupta, Márton L. Tóth, Siva A. Vanapalli, Aldo Jongejan, Morten Scheibye‐Knudsen, Riekelt H. Houtkooper, Georges E. Janssens

The paper identifies atracurium as an FDA-approved compound that extends lifespan and healthspan in C. elegans by activating the FOXO/DAF-16 longevity pathway through neuromuscular acetylcholine receptor inhibition.

Aging Cell · Jul 6, 2021Peer-reviewedMolecular Biology

Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion

Yasmine J. Liu, Georges E. Janssens, Rebecca L. McIntyre, Marte Molenaars, Rashmi Kamble, Arwen W. Gao, Aldo Jongejan, Michel van Weeghel, Alyson W. MacInnes, Riekelt H. Houtkooper

This study shows glycine supplementation extends C. elegans lifespan and alters gene expression, with effects dependent on the methionine cycle.

PLoS Genetics · Mar 7, 2019Peer-reviewedSystems Biology

Natural genetic variation in C. elegans reveals genomic loci controlling metabolite levels

Arwen W. Gao, Mark G. Sterken, Jelmi uit de Bos, Jelle van Creij, Rashmi Kamble, Basten L. Snoek, Jan E. Kammenga, Riekelt H. Houtkooper

The paper identifies genetic loci controlling metabolite levels in C. elegans using recombinant inbred lines and QTL mapping.

Genome Research · Sep 1, 2018Peer-reviewedGenomics