Branko Stefanovic

The paper identifies a contaminant in cefixime, ATO-OA, as a potent inhibitor of LARP6/5SL interaction, showing antifibrotic effects in vitro and in organoids.

This study shows LARP6 regulates fibrogenic gene translation in liver fibrosis by interacting with collagen mRNAs and reducing fibrosis in human HSCs.

This study quantifies the mechanical dynamics of GBM neurosphere invasion in 3D Matrigel, identifying key roles for actomyosin contractility and microtubules in invasion.

This study identifies the RNK motif in LARP6's La-domain as critical for sequence-specific binding to the 5SL of collagen mRNAs, suggesting it as a target for antifibrotic drug design.