Author

Wusheng Xiao

Brigham and Women's HospitalORCID 0000-0002-0256-8746Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Bradley M. WertheimiD· 1 shared Clary B. ClishiD· 1 shared Elena AronsiD· 1 shared Huamei He· 1 shared Jane A. LeopoldiD· 1 shared Joseph LoscalzoiD· 1 shared Marcia C. HaigisiD· 1 shared Nishith M. ShrimaliiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Bradley M. WertheimORCID

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1 paper

Recent·Most cited

Branched chain α-ketoacids aerobically activate HIF1α signaling in vascular cells

Wusheng Xiao, Nishith M. Shrimali, Niv Vigder, William M. Oldham, Clary B. Clish, Huamei He, Samantha J. Wong, Bradley M. Wertheim, Elena Arons, Marcia C. Haigis, Jane A. Leopold, Joseph Loscalzo

This study identifies branched chain α-ketoacids (BCKAs) as novel signaling metabolites that activate HIF1α signaling in normoxia and modulate vascular smooth muscle cell function in pulmonary vascular disease.

Nature Metabolism · Oct 29, 2024Peer-reviewedCell Biology