Christian Thomas Mayer

Distributed Clonal Deletion Prevents Autoimmune Disease Progression

This study shows that distributed clonal deletion checkpoints prevent autoimmune disease by restricting autoreactive B cell diversification and persistence.

Scalable generation of pure CD103⁺ cDC1 from iDC1 cultures

This paper develops a scalable method to generate pure CD103+ cDC1 from mouse bone marrow cultures, achieving high purity and yield for immunological studies.

Affinity maturation of antibody responses is mediated by differential plasma cell proliferation

The paper shows that high-affinity B cells divide more and receive more Tfh help, leading to affinity maturation in plasma cells.