PhysiologyAging CellPeer-reviewed
Chronic activation of a key exercise signal transducer, CaMKII, drives skeletal muscle aging and sarcopenia
Michael R. Bene, Tae Chung, Elizabeth D. Luczak…·Qinchuan Wang
This study shows chronic CaMKII activation drives skeletal muscle aging and sarcopenia, and partial inhibition in aged muscle improves function and shifts the transcriptome toward a youthful state.
DOI 10.1111/acel.70704