Author

Yifan Deng

Fudan UniversityORCID 0000-0002-0334-4760Unclaimed ORCID profile · follow to get notified of new preprints

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Yifan Deng1 paper

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jiasong Pan· 3 shared Jixi LiiD· 3 shared Lu GengiD· 3 shared Suhua LiiD· 2 shared Xuehe Liu· 2 shared Yajie Shen· 2 shared Adi IdrisiD· 1 shared Bao-Xue GeiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersNeuroscience

Jiasong Pan

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3 papers

Recent·Most cited

Gasdermin E couples mitochondrial damage to pyroptotic neurodegeneration in Parkinson disease

Jiasong Pan, Lu Geng, Xuehe Liu, Yinglei Wang, Ning Fang, Feiyan Xie, Yajie Shen, Yifan Deng, Yuyun Han, Suhua Li, Wenyong Xiong, Hua He, Ning‐Yi Shao, Jian Wang, Jixi Li

This paper identifies GSDME as a mediator of neurodegeneration in Parkinson's disease by linking mitochondrial damage to pyroptotic cell death through caspase-3 activation.

bioRxiv · Dec 16, 2025 · PreprintNeuroscience

Peptides alleviate cognitive impairment by inhibiting and disassembling amyloid-beta aggregates in Alzheimer disease

Wenqing Gao, Baocai Gao, Sen Wang, Di Wu, Pucheng Mei, Lu Geng, Chuhao Li, Yuanyuan Li, Xuehe Liu, Jiasong Pan, Jing Huang, Yifan Deng, Xiangjun Chen, Hexige Saiyin, Hongbo Yu, , Jixi Li

The paper shows that specific peptides inhibit Aβ aggregation and reduce cognitive impairment in Alzheimer's disease models.

bioRxiv · May 28, 2025 · PreprintNeuroscience

RING1 dictates GSDMD-mediated inflammatory response and host susceptibility to pathogen infection

Yuanyuan Li, Wenqing Gao, Yuxin Qiu, Jiasong Pan, Qingqing Guo, Xuehe Liu, Lu Geng, Yajie Shen, Yifan Deng, Zhidong Hu, Suhua Li, Shanshan Liu, Adi Idris, Jinqing Huang, Hua Yang, , Jixi Li

This study shows RING1 suppresses pyroptosis by ubiquitinating GSDMD, reducing inflammation and pathogen susceptibility in mice.

Cell Death and Differentiation · May 14, 2025Peer-reviewedCell Biology