Author

Chelsea A. Vadnie

Ohio Wesleyan UniversityORCID 0000-0002-0374-4035Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Colleen A. McClungiD· 4 shared Kaitlyn A. Petersen· 4 shared Jennifer N. BurnsiD· 3 shared Lauren M. DePoyiD· 3 shared Madeline R. ScottiD· 3 shared Aaron K. JenkinsiD· 2 shared George C. TsengiD· 2 shared Allison J. Cerwensky· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersNeuroscience

Colleen A. McClungORCID

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4 papers

Recent·Most cited

Prenatal circadian rhythm disruption induces sex-specific substance use and mood-related phenotypes in mice

Nilanjana Saferin, Taylor Ashley Stowe, Chelsea A. Vadnie, Kaitlyn A. Petersen, Madeline R. Scott, Emily Chen, Lucia Bustos-Robles, Riley Griffin, Colleen A. McClung, Lauren M. DePoy

This study shows that prenatal circadian rhythm disruption in mice leads to sex-specific behavioral changes in adulthood, with females showing mood-related issues and males showing substance use-like behaviors.

bioRxiv · Jun 28, 2026 · PreprintNeuroscience

Molecular and cellular rhythms in excitatory and inhibitory neurons in the mouse prefrontal cortex

Jennifer N. Burns, Aaron K. Jenkins, RuoFei Yin, Wei Zong, Lauren M. DePoy, Kaitlyn A. Petersen, Mariya Kaminsky, Chelsea A. Vadnie, Madeline R. Scott, George C. Tseng, Yanhua H. Huang, Colleen A. McClung

This study identifies cell-type and sex-specific gene expression and electrophysiological rhythms in mouse prefrontal cortex neurons, showing differences in rhythmic transcripts and biological processes between excitatory pyramidal cells and inhibitory PV interneurons.

Cerebral Cortex · Jul 1, 2025Peer-reviewedNeuroscience

Comparative transcriptomic rhythms in the mouse and human prefrontal cortex

Jennifer N. Burns, Aaron K. Jenkins, Xiangning Xue, Kaitlyn A. Petersen, Kyle D. Ketchesin, Megan S. Perez, Chelsea A. Vadnie, Madeline R. Scott, Marianne L. Seney, George C. Tseng, Colleen A. McClung

This study compares circadian transcriptomic rhythms in mouse and human prefrontal cortex subregions, finding conserved signaling with sex-specific phase shifts and species-specific rhythmic transcript identities.

Frontiers in Neuroscience · Jan 13, 2025Peer-reviewedNeuroscience

The Suprachiasmatic Nucleus Regulates Anxiety-Like Behavior in Mice

Chelsea A. Vadnie, Kaitlyn A. Petersen, Lauren A. Eberhardt, Mariah A. Hildebrand, Allison J. Cerwensky, Hui Zhang, Jennifer N. Burns, Darius D. Becker‐Krail, Lauren M. DePoy, Ryan Wellington Logan, Colleen A. McClung

This study shows that manipulating SCN neural activity in mice affects anxiety-like behavior but not depressive-like behavior, with dampened activity rhythms correlating with increased anxiety.

Frontiers in Neuroscience · Jan 20, 2022Peer-reviewedNeuroscience