Author

Zhenning Wang

Shanghai Medical College of Fudan UniversityORCID 0000-0002-0391-1534Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Aixia SongiD· 2 shared Fei CheniD· 2 shared Bolin Tao· 1 shared Congling XuiD· 1 shared Hai JiangiD· 1 shared Hai ZhengiD· 1 shared Huijuan YangiD· 1 shared Jiwei CheniD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

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10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Aixia SongORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 7, 2024

Catalytic-independent functions of INTAC in conferring sensitivity to BET inhibition

Pengyu Fan, Xue-Ying Shang, Aixia Song…·Fei Chen

The paper identifies that BET inhibitor efficacy depends on the INTAC complex's auxiliary module, which interacts with the RACK7/ZMYND8-KDM5C complex to remove H3K4 methylation, thereby restoring sensitivity to BET inhibitors through WDR5 degradation.

2 citations

humanChIP-seq

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Molecular BiologybioRxivPreprintNov 28, 2022

H3K4 di- and trimethylation modulate the stability of RNA polymerase II pausing

Shibin Hu, Aixia Song, Linna Peng…·Fei Chen

This study shows that H3K4me3 dynamics regulate RNA polymerase II pausing through interactions with the INTAC termination complex and Pol II elongation.

1 citation

humanChIP-seq

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