Cell BiologybioRxivPreprint
Hierarchical membrane-chromatin tethering buffers nuclear envelope assembly against alterations in lipid flux
Sarah R. Barger, Sofia Sepùlveda, Yang Han…·Shirin Bahmanyar
The paper shows that hierarchical membrane-chromatin tethering, specifically involving LEM-2 and Emerin, ensures nuclear envelope stability by regulating lipid homeostasis and preventing abnormal nuclear morphology.
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