Ryan Arathimos

This study investigates the genetic relationship between depression symptoms and Alzheimer's disease using GWAS and finds significant genetic correlations but no causal link, suggesting proxy cases may drive the overlap.

This study uses genomic PCA to identify shared genetic architecture between brain morphometry, ageing, and cognitive ability using UK Biobank data.

This study investigates the relationship between early life stressors and adult mental health through methylome-wide association studies, finding no evidence of methylome mediation but linking birth date to blood cell type composition.

This study uses multiple depression measures to improve the validity of Major Depressive Disorder cases in the UK Biobank, finding increased genetic contribution with more measures.

The paper identifies three loci where genetic liability to non-syndromic cleft lip/palate may be mediated by DNA methylation variation in blood and tissue.

Combining nearby CpG summary statistics by inverse-variance weighted meta-analysis holds false positives at the nominal level where comb-p and DMRcate inflate, and supports multi-cohort meta-analysis.