Meea Fogal

This study shows that non-homologous end joining (NHEJ) facilitates rapid adaptation to caspofungin in Nakaseomyces glabratus by enabling FKS2 mutations, while NHEJ-deficient strains adapt less efficiently through alternative pathways.

The paper uses CRISPR screening to identify secretory pathway genes that drive antifungal tolerance through aneuploidy in Candida albicans.

This study uses pooled CRISPRi screening in Candida albicans to identify dosage-sensitive genes across diverse environments and genetic backgrounds, highlighting potential antifungal targets.

This paper uses CRISPR-Cas9 to induce targeted loss of heterozygosity in Candida albicans and validates its role in antifungal resistance.