Jussi Kupari

The paper shows that TRPV1+ afferents rapidly reprogram TRPV1- Aβ afferents, leading to hyperalgesia in humans.

This paper constructs a human dorsal root ganglion reference atlas, identifying 22 neuronal subtypes and 10 non-neuronal cell types, and reveals functional differences between human and mouse DRG neurons.

The paper identifies distinct neural ensembles in mouse spinal cord encoding mechanical and heat pain and shows their role in affective pain behavior.

The paper identifies persistent interferon signaling via the MNK1/2-eIF4E pathway as a driver of sensory neuron plasticity and pain in arthritis.

This study develops a method to sequence individual human DRG neuron somas, identifies 16 neuronal types, and reveals human-specific nociceptor types and potential drug targets.

The paper identifies primate sensory neuron types associated with human chronic pain using transcriptomics and maps human pain heritability to these neuronal types.

This study shows that excess fetal GDNF can prolong nephrogenesis in postnatal mouse kidneys without increasing tumor risk.