Author
The University of Texas at San Antonio Health Science CenterORCID 0000-0002-3441-9673Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Qiujun Yu, Yonghui Zhao, Joshua M Maurer, Prakash Arullampalam, Nathaniel John, John D. Tranter, Tarek Mohamed Abd El‐Aziz, Michelle Lin, Daniel J. Lerner, Carmen M. Halabi, Rajan Sah
This study identifies LRRC8C as a non-redundant component of the endothelial LRRC8 complex that regulates vascular reactivity and blood pressure.
Hypertension · Feb 4, 2026Peer-reviewedCell Biology
John D. Tranter, Ryan T. Mikami, Ashutosh Kumar, Gavriel Brown, Tarek Mohamed Abd El‐Aziz, Yonghui Zhao, Prakash Arullampalam, Katrina J. Ashworth, Vishwanath Jha, Nihil Abraham, Chloe Grace Meyer, Abigail Ajanel, Litao Xie, Yongmei Feng, Juan Hong, , Rajan Sah
This study identifies LRRC8 complexes as ATP/ADP release channels in platelets that regulate thrombosis by modulating calcium and PI3K-AKT signaling through P2X1, P2Y1, and P2Y12 receptors.
Blood · Jun 20, 2025Peer-reviewedCell Biology
Sk. Sarif Hassan, Vaishnavi Kodakandla, Elrashdy M Moustafa Mohamed Redwan, Kenneth H. Lundstrom, Pabitra Pal Choudhury, Tarek Mohamed Abd El‐Aziz, Kazuo Takayama, Ramesh J. L. Kandimalla, Amos Lal, Ángel Serrano‐Aroca, Gajendra Kumar Azad, Alaa A. A. Aljabali, Giorgio Palù, Gaurav Chauhan, Parise Adadi, , Vladimir Nikolaevich Uversky
The paper identifies 47 unique truncated ORF8 protein variants in B.1.1.7 SARS-CoV-2 sequences and defines nine possible variants based on physicochemical properties.
PeerJ · Mar 21, 2022Peer-reviewedBioinformatics
Sk. Sarif Hassan, Kenneth H. Lundstrom, Debmalya Barh, Raner José Santana Silva, Bruno Silva Andrade, Vasco Azevedo, Pabitra Pal Choudhury, Giorgio Palù, Bruce D. Uhal, Ramesh J. L. Kandimalla, Murat Seyran, Amos Lal, Samendra P. Sherchan, Gajendra Kumar Azad, Alaa A. A. Aljabali, , Vladimir Nikolaevich Uversky
The paper analyzes S-protein variants of SARS-CoV-2 from six continents, finding North America has the most unique variants, which may spread globally, suggesting travel restrictions and vaccine updates are needed.
International Journal of Biological Macromolecules · Sep 24, 2021Peer-reviewedBioinformatics
Sk. Sarif Hassan, Diksha Attrish, Shinjini Ghosh, Pabitra Pal Choudhury, Vladimir Nikolaevich Uversky, Alaa A. A. Aljabali, Kenneth H. Lundstrom, Bruce D. Uhal, Nima Rezaei, Murat Seyran, Damiano Pizzol, Parise Adadi, Antonio Garcia Soares, Tarek Mohamed Abd El‐Aziz, Ramesh J. L. Kandimalla, , Adam Brufsky
The paper analyzes sequence variations and structural properties of SARS-CoV-2 ORF10 protein to assess its role in viral pathogenicity and potential as a pharmaceutical target.
International Journal of Biological Macromolecules · Apr 16, 2021Peer-reviewedBioinformatics
Sk. Sarif Hassan, Alaa A. A. Aljabali, Pritam Kumar Panda, Shinjini Ghosh, Diksha Attrish, Pabitra Pal Choudhury, Murat Seyran, Damiano Pizzol, Parise Adadi, Tarek Mohamed Abd El‐Aziz, Antonio Garcia Soares, Ramesh J. L. Kandimalla, Kenneth H. Lundstrom, Amos Lal, Gajendra Kumar Azad, , Murtaza M. Tambuwala
This study analyzes the ORF8 protein of SARS-CoV-2 and its mutations across human, bat, and pangolin hosts to understand its role in immune evasion and evolutionary dynamics.
Computers in Biology and Medicine · Apr 15, 2021Peer-reviewedMolecular Biology
Sk. Sarif Hassan, Shinjini Ghosh, Diksha Attrish, Pabitra Pal Choudhury, Vladimir Nikolaevich Uversky, Bruce D. Uhal, Kenneth H. Lundstrom, Nima Rezaei, Alaa A. A. Aljabali, Murat Seyran, Damiano Pizzol, Parise Adadi, Antonio Garcia Soares, Tarek Mohamed Abd El‐Aziz, Ramesh J. L. Kandimalla, , Adam Brufsky
The paper analyzes ACE2 receptors across nineteen species to propose a possible SARS-CoV-2 transmission flow based on receptor-binding domain interactions.
Molecules · Dec 13, 2020Peer-reviewedBioinformatics
Sk. Sarif Hassan, Pabitra Pal Choudhury, Vladimir Nikolaevich Uversky, Guy W. Dayhoff, Alaa A. A. Aljabali, Bruce D. Uhal, Kenneth H. Lundstrom, Nima Rezaei, Murat Seyran, Damiano Pizzol, Parise Adadi, Amos Lal, António Soares, Tarek Mohamed Abd El‐Aziz, Ramesh J. L. Kandimalla, , Adam Brufsky
The paper analyzes variations in SARS-CoV-2 accessory proteins across global proteomes and finds ORF3a has the highest unique variations, suggesting these variations may influence pathogenicity.
bioRxiv · Nov 6, 2020 · PreprintBioinformatics