Author

Xun Chen

Nanjing Medical UniversityORCID 0000-0002-0601-8397Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xun Chen3 papers · University of Freiburg

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Feng HaniD· 1 shared Gijs J. L. WuiteiD· 1 shared Jie Zhang· 1 shared Longfu XuiD· 1 shared Meindert Hugo LamersiD· 1 shared Mia UremiD· 1 shared Nan JiangiD· 1 shared Peter Guy WolynesiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

Feng HanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Ourotide: decoding the hierarchical peptide recognition for generative design

Yuhang Shen, Jie Zhang, Zhouyue Wu, Ziyan Xing, Qiuyu Yuan, Wen Zhang, Qigang Zhou, Feng Han, Nan Jiang, Xun Chen

The paper introduces Ourotide, a deep learning framework for peptide recognition that outperforms generalist models by capturing a unique hierarchical binding mode through physics-guided data augmentation.

bioRxiv · Sep 16, 2026 · PreprintBioinformatics

DNA polymerase actively and sequentially displaces single-stranded DNA-binding proteins

Longfu Xu, Shikai Jin, Mia Urem, Seung‐Joo Lee, Meindert Hugo Lamers, Xun Chen, Peter Guy Wolynes, Gijs J. L. Wuite

This study investigates how DNA polymerase displaces SSBs during replication, showing sequential displacement and the role of SSB saturation in replication efficiency.

Nature Communications · Aug 12, 2025Peer-reviewedBiophysics