Author

Chris Grant

University of ManchesterORCID 0000-0002-0616-6576Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Chris Grant2 papers · Public Health Agency of Canada

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alex Anderton· 1 shared Andrew Michael FreyiD· 1 shared Christian HackeriD· 1 shared Colin RickmaniD· 1 shared Flávia M. ZimbresiD· 1 shared Genady PankoviD· 1 shared Ian LeavesiD· 1 shared Janet QuinniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alex Anderton

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2 papers

Recent·Most cited

The yeast Gcn2 protein kinase mediates P-body formation both through its activity with eIF2α and with non-canonical substrates

Viktoras Stonys, Simon Hubbard, Mark Peter Ashe, Chris Grant

This study shows that yeast Gcn2 promotes P-body formation through eIF2α phosphorylation and Smu2-dependent mRNA granule maturation, even when eIF2α phosphorylation is blocked.

bioRxiv · Nov 9, 2026 · PreprintCell Biology

The Type VI Secretion System Antifungal Effector Tfe2 Inhibits Protein Translation and Drives Hyperactivation of TORC1.

Katharina Trunk, Genady Pankov, Alex Anderton, Viktoras Stonys, Andrew Michael Frey, Jennifer H. Haggarty, Ian Leaves, Pantelitsa Papakyriacou, Mengchun Li, Vivek Manthri, Flávia M. Zimbres, Paul William Denny, Phillip D. Whitfield, Christian Hacker, Neil A. R. Gow, , Janet Quinn

This study identifies Tfe2 as a novel antifungal effector that inhibits protein translation and hyperactivates TORC1, leading to cellular remodeling in yeast.

bioRxiv · Nov 20, 2025 · PreprintMicrobiology