DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairment
Ran‐Der Hwang, Yuning Lu, Qing Tang, Goran Periz, Giho Park, Xiangning Li, Qiwang Xiang, Yang Liu, Tao Zhang, Jiou Wang
The paper identifies DBT as a metabolic regulator that suppresses proteotoxicity by enhancing ubiquitinated protein clearance under proteasomal impairment.
eLife · Sep 10, 2024Peer-reviewedNeuroscience