Author

Yang Liu

University of Wisconsin–MadisonORCID 0000-0002-5472-6080Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yang Liu45 papers · BGI Group (China)

Biology Disciplines

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Physiology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Cara L. GreeniD· 2 shared Dudley W. LammingiD· 2 shared Isaac Grunow· 2 shared Mariah F. CalubagiD· 2 shared Michelle M. SonsallaiD· 2 shared Reji BabygirijaiD· 2 shared Alan D. Attie· 1 shared Anna Tobon· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersPhysiology

Cara L. GreenORCID

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3 papers

Recent·Most cited

Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice

Mariah F. Calubag, Ismail Ademi, Cara L. Green, Dulmalika N. H. Manchanayake, Hashan S. M. Jayarathne, Ryan N. Marshall, Sandra M. Le, Penelope Lialios, Lucia E. Breuer, Shoshana Yakar, Reji Babygirija, Michelle M. Sonsalla, Isaac Grunow, Chung-Yang Yeh, Yang Liu, , Dudley W. Lamming

This study shows that lifelong dietary valine restriction improves healthspan and extends lifespan in male mice but not females, with distinct molecular effects in different tissues.

Nature Aging · Jul 24, 2026Peer-reviewedPhysiology

Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer&aposs disease

Reji Babygirija, Jessica H. Han, Michelle M. Sonsalla, Ryan Matoska, Mariah F. Calubag, Cara L. Green, Anna Tobon, Chung‐Yang Yeh, Diana Vertein, Sophia Schlorf, Julia Illiano, Yang Liu, Isaac Grunow, Michael J. Rigby, Luigi Puglielli, , Dudley W. Lamming

This study shows that fasting, not just calorie reduction, is necessary for many benefits of caloric restriction in 3xTg mice with Alzheimer's disease.

Nature Communications · Aug 4, 2025Peer-reviewedPhysiology

DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairment

Ran‐Der Hwang, Yuning Lu, Qing Tang, Goran Periz, Giho Park, Xiangning Li, Qiwang Xiang, Yang Liu, Tao Zhang, Jiou Wang

The paper identifies DBT as a metabolic regulator that suppresses proteotoxicity by enhancing ubiquitinated protein clearance under proteasomal impairment.

eLife · Sep 10, 2024Peer-reviewedNeuroscience