Author

Yuning Lu

Johns Hopkins UniversityORCID 0000-0002-8176-2108Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yuning Lu1 paper · University of Cambridge

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Jiou WangiD· 3 shared Haocheng WangiD· 2 shared Qiwang XiangiD· 2 shared Tao ZhangiD· 2 shared Andrew S PekosziD· 1 shared Camille Wouters· 1 shared Giho ParkiD· 1 shared Goran PeriziD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCell Biology

Jiou WangORCID

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3 papers

Recent·Most cited

Noncanonical amino acid incorporation enables minimally disruptive labeling of stress granule and TDP-43 proteinopathy

Hao Chen, Haocheng Wang, Yuning Lu, Peng Chen, Zhongfan Zheng, Tao Zhang, Jiou Wang

This study uses a noncanonical amino acid to label stress granule and TDP-43 proteins with minimal disruption, showing accurate localization and dynamics in live cells.

eLife · Jul 3, 2026Peer-reviewedCell Biology

Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus

Qiwang Xiang, Camille Wouters, Peixi Chang, Yuning Lu, Mingming Liu, Haocheng Wang, Haley Heine, Sunning Qian, Junqin Yang, Andrew S Pekosz, Yan‐Jin Zhang, Jiou Wang

This study identifies ITCH as a key regulator of SARS-CoV-2 life cycle, showing it enhances virion assembly and secretion while suppressing spike protein cleavage, and demonstrates that ITCH inhibition reduces viral replication.

eLife · May 29, 2026Peer-reviewedMolecular Biology

DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairment

Ran‐Der Hwang, Yuning Lu, Qing Tang, Goran Periz, Giho Park, Xiangning Li, Qiwang Xiang, Yang Liu, Tao Zhang, Jiou Wang

The paper identifies DBT as a metabolic regulator that suppresses proteotoxicity by enhancing ubiquitinated protein clearance under proteasomal impairment.

eLife · Sep 10, 2024Peer-reviewedNeuroscience