Author

Kentaro Hirose

University of California, San FranciscoORCID 0000-0002-0634-3173Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:ChIP-seq· 1 Organism:human· 1

Frequent Co-Authors

Guo N. HuangiD· 3 shared Alberto MalerbaiD· 1 shared Alexander Y. PayumoiD· 1 shared Alexis BoulinguieziD· 1 shared Catarina Maria QuinziiiD· 1 shared Di LangiD· 1 shared Emanuele BarcaiD· 1 shared Guang HuiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersDevelopmental Biology

Guo N. HuangORCID

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3 papers

Recent·Most cited

Chromatin topology control by a muscle-specific ribosomal protein

Makoto Nakamura, Xiaoxin Chen, Shun Yao, Lynette Xin Chan, Ruan Hongmei, Alexis Boulinguiez, Nav Lally, Hao Wu, Kara Kodani, Kentaro Hirose, James P. Pirruccello, Alberto Malerba, Yifan Cheng, Vasanth Vedantham, Longzhi Tan, , Guo N. Huang

This study identifies Rpl3l as a muscle-specific ribosomal protein that regulates chromatin insulation in atrial cardiomyocytes, linking genome structure to cardiac rhythm stability.

bioRxiv · Jun 26, 2026 · PreprintPhysiology

Loss of a novel striated muscle-enriched mitochondrial protein Coq10a enhances postnatal cardiac hypertrophic growth

Kentaro Hirose, Steven Chang, Hongyao Yu, Jiajia Wang, Emanuele Barca, Xiaoxin Luke Chen, Sheamin Khyeam, Kazuki Tajima, Takeshi Yoneshiro, Shingo Kajimura, Catarina Maria Quinzii, Guang Hu, Guo N. Huang

This study shows that loss of Coq10a, a muscle-enriched mitochondrial protein, enhances postnatal cardiac hypertrophy without impairing cardiac function.

bioRxiv · Sep 3, 2019 · PreprintDevelopmental Biology

Sympathetic Nerve Activity Promotes Cardiomyocyte Cell-Cycle Arrest And Binucleation

Li Chen, Alexander Y. Payumo, Kentaro Hirose, Rachel B. Bigley, Jonathan Lovas, Rejji Kuruvilla, Guo N. Huang

This study shows that sympathetic nerve activity reduces cardiomyocyte proliferation and causes binucleation, which may limit heart regeneration in adults.

bioRxiv · Apr 5, 2017 · PreprintDevelopmental Biology