Author

Shun Yao

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alberto MalerbaiD· 1 shared Alexis BoulinguieziD· 1 shared Christian G. Cerda-SmithiD· 1 shared Dale A. RamsdeniD· 1 shared Di LangiD· 1 shared Fu YangiD· 1 shared Fuming Li· 1 shared Guo N. HuangiD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperPhysiology

Alberto MalerbaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Chromatin topology control by a muscle-specific ribosomal protein

Makoto Nakamura, Xiaoxin Chen, Shun Yao, Lynette Xin Chan, Ruan Hongmei, Alexis Boulinguiez, Nav Lally, Hao Wu, Kara Kodani, Kentaro Hirose, James P. Pirruccello, Alberto Malerba, Yifan Cheng, Vasanth Vedantham, Longzhi Tan, , Guo N. Huang

This study identifies Rpl3l as a muscle-specific ribosomal protein that regulates chromatin insulation in atrial cardiomyocytes, linking genome structure to cardiac rhythm stability.

bioRxiv · Jun 26, 2026 · PreprintPhysiology

BRCA1-A and LIG4 complexes mediate ecDNA biogenesis and cancer drug resistance

Oliver W. Chung, Shun Yao, Ling Wang, Fu Yang, Lauren Schier, Melissa Aldana, Christian G. Cerda-Smith, Haley M. Hutchinson, Kris C. Wood, Weijia Su, Mustafa Khasraw, Lee Zou, Dale A. Ramsden, ZZ Zhao Zhang

This study identifies BRCA1-A and LIG4 complexes as mediators of ecDNA biogenesis and shows their role in cancer drug resistance.

Proceedings of the National Academy of Sciences · Mar 11, 2026Peer-reviewedCancer Biology

Lysyl oxidase inhibition drives the transdifferentiation from lung adenocarcinoma to squamous cell carcinoma in mice

Shun Yao, Xiangkun Han, Xinyuan Tong, Fuming Li, Zhen Qin, Hsin-Yi Huang, Ji Hongbin

This study shows that lysyl oxidase inhibition in a mouse model drives lung adenocarcinoma to squamous cell carcinoma transdifferentiation, independent of LKB1 status.

bioRxiv · Jun 10, 2018 · PreprintCancer Biology