Peter Soba

The paper identifies RHODOPSIN 7 as a non-canonical light sensor in Drosophila that influences behavior and shows its evolutionary origins across panarthropods.

The paper shows that Dh44 and Ilp7 neurons in Drosophila larvae mediate metabolic state-dependent behavioral decisions in conflicting sensory contexts by regulating light tolerance.

This study characterizes AkVAL, a bistable opsin from the flashlight fish, showing its ability to control neuronal activity and body movement in response to light cycles, suggesting its potential as an optogenetic tool.

The paper shows that lipid imbalances in a Drosophila model of PME8 cause dendrite loss and that restoring specific ceramides while reducing bioactive lipids rescues the phenotype.

The paper identifies cytokine signaling from neurons to glia as a key determinant in axon length-dependent vulnerability in fly models of human neurodegenerative disorders.

This paper identifies PdCO as a bistable GPCR with high temporal precision for optogenetic control of neural circuits in vivo.

The paper identifies neural circuits in Drosophila larvae that mediate context-dependent competition between defensive actions like startle and escape behaviors.

This paper optimizes optogenetically functionalized GPCRs to achieve specific in vivo neuromodulatory signaling in Drosophila, showing rescue of endogenous receptor function.

The paper introduces Aion, a bistable anion-conducting channelrhodopsin with a long open state and precise light-switchable control, enabling extended neuronal silencing in Drosophila.

BiPOLES is an optogenetic tool that allows bidirectional control of neuronal activity using two different light colors, enabling both excitation and inhibition of the same neurons in a single experiment.

This paper demonstrates optogenetic delivery of trophic signals using light-activated receptors to suppress disease phenotypes in Parkinson's disease models.

This paper introduces eOPN3, a modified mosquito rhodopsin that suppresses synaptic transmission with high spatiotemporal precision in vivo.

The paper identifies a somatosensory network in Drosophila larvae that uses neuropeptide action to gate specific escape behaviors based on sensory input type.

The paper shows that Tao kinase regulates synaptic growth and connectivity in Drosophila nociceptive circuits to maintain specificity and function during larval development.

The paper engineers anion-conducting channelrhodopsins with tunable spectra and kinetics for optogenetic control of behavior.