Author

Sheng Zhang

First Affiliated Hospital of Fujian Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

Ailing W. ScottiD· 1 shared Anthony PompettiiD· 1 shared Christopher P. VellanoiD· 1 shared Curt BalchiD· 1 shared Di Chen· 1 shared Dipti AthavaleiD· 1 shared Emilio CirriiD· 1 shared Emma C. WheeleriD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

Ailing W. ScottORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Bone Mechanosensing Dictates Hematopoietic Stem Cell Fate and Immune Homeostasis

Wuju Zhang, Yating Pan, Xiaoling Xie, Jianmeng Du, Huihui Zhang, Z L Ye, Xiaoqing Yan, 黄炯竑, Hailin Jing, Sheng Zhang, Xiaolin Liu, Di Chen, Ying Liu, Xiao Hong Yu, Xiaochun Bai

This study shows that bone mechanosensing influences HSC fate and immune homeostasis by directing lymphoid or myeloid differentiation through Piezo1-dependent pathways.

bioRxiv · Jul 9, 2026 · PreprintImmunology

Transient protein phosphorylation promotes disease tolerance to sepsis

Wolfgang Vivas, Johannes Roth, Katharina Willman, Hjalmar R. Bouma, Franziska Röstel, Karen Dlubatz, Gianna Hirth, Nadine Pömpner, Therese Dau, Emilio Cirri, Sheng Zhang, Mirko Peitzsch, Triantafyllos Chavakis, Michael W Bauer, Gianni Pannagiotou, , Sebastian Weis

This paper identifies transient GSK3β activation as a mechanism promoting disease tolerance to sepsis through hypometabolism, without affecting pathogen burden.

bioRxiv · Jun 10, 2026 · PreprintImmunology

A genetic tool targeting brain GPR75

Emma C. Wheeler, Runzhou Yang, Stephen Matthew Farmer, Sheng Zhang, Ningyan Zhang, Zhiqiang An, Qingchun Tong

The paper develops a GPR75-GFP-Ires-Cre knockin mouse strain to study GPR75's role in diet-induced obesity by visualizing its brain expression and function.

bioRxiv · Jun 2, 2026 · PreprintNeuroscience

YAP1 Depletion Enhances TAZ and its Complexation with TEAD4 and AP-1 Heterodimer C-JUN/FOSB to Promote Gastric Cancer Progression and Metastases

Jingjing Wu, Dipti Athavale, Curt Balch, Junsong Zhao, Gengyi Zou, Yibo Fan, Yan-ting Yann Zhang, Joseph Jonathan Zhao, Mikel D. Ghelfi, Anthony Pompetti, Gennaro Calendo, Ailing W. Scott, Shan Shao, Xiao-Dan Yao, Melissa Pool Pizzi, , Shumei Song

This study shows that inhibiting both YAP1 and TAZ in gastric cancer peritoneal metastases reduces tumor growth and progression by blocking their interactions with TEAD4 and AP-1 complexes.

bioRxiv · Nov 13, 2025 · PreprintCancer Biology