Author

Gang Zheng

University Health NetworkORCID 0000-0002-0705-7398Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Adam DowleiD· 1 shared Alexandra Misura· 1 shared Andrew N. HoldingiD· 1 shared Arturo Israel Machuca‐ParraiD· 1 shared August LiniD· 1 shared Christopher F. RoseiD· 1 shared David KealyiD· 1 shared Dianne E. Chadwick· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Adam DowleORCID

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2 papers

Recent·Most cited

Covalently Functionalized Click Alginate Cryogels Enable Non-Invasive Near-Infrared Sensing of Gastric pH

Katia Cherifi, Arturo Israel Machuca‐Parra, Lili Ding, Nahyun Kwon, Loic Bart, Mouna Ayad, Christopher F. Rose, Gang Zheng, Simon Matoori

This paper develops a non-invasive gastric pH sensor using covalently functionalized click alginate cryogels that remain stable in acidic and protease-rich environments and accurately detect pH changes in vivo.

bioRxiv · Sep 18, 2026 · PreprintBioengineering

Aberrant splicing of MBD1 reshapes the epigenome to drive convergent myeloerythroid defects in MDS

He Tian Chen, Pratik Joshi, Séverine Cathelin, Soheil Jahangiri, Saeer A Adeel, Joshua Xu, Emily Tsao, Yulin Mo, David Kealy, Adam Dowle, Zaldy Balde, Marry Xuan, Dylan Gowlett-Park, Katarina Czibere, Alexandra Misura, , Kristin J. Hope

This study identifies MBD1-L, an aberrantly spliced transcript in MDS, which drives epigenetic changes leading to myeloerythroid defects, and shows ASO-based targeting can restore erythroid differentiation.

Blood · Jun 20, 2026Peer-reviewedCancer Biology