André Pires‐daSilva

Massive programmed DNA elimination during embryogenesis in the trioecious nematode Auanema rhodense

The paper reports extreme programmed DNA elimination in Auanema rhodense during embryogenesis, revealing extensive loss of germline-specific DNA from somatic cells.

The contribution of an X chromosome QTL to non-Mendelian inheritance and unequal chromosomal segregation in A. freiburgense

The paper identifies an X chromosome QTL associated with non-Mendelian inheritance and nullo-spermatid elimination in A. freiburgense.

The X chromosome is a potential polarising signal for asymmetric cell divisions in meiotic cells of a nematode

The paper identifies the X chromosome as a polarising signal for asymmetric cell division in nematode meiotic cells, where it directs the segregation of essential sperm components.

Chromatin-associated effectors of energy-sensing pathways mediate intergenerational effects

The paper shows that parental modulation of nutrient-sensing pathways in nematodes affects offspring phenotypic plasticity through chromatin-associated effectors.

Towards genetic modification of plant-parasitic nematodes: delivery of macromolecules to adults and expression of exogenous mRNA in second stage juveniles.

This paper develops methods for delivering macromolecules and expressing exogenous mRNA in plant-parasitic nematodes, advancing functional genetic tools for these pests.

Liposome-based transfection enhances RNAi and CRISPR-mediated mutagenesis in non-model nematode systems

The paper demonstrates that liposome-based transfection combined with microinjection enables reliable RNAi and CRISPR-mediated mutagenesis in non-model nematodes.

Chromosome-wide evolution and sex determination in a nematode with three sexes

This study reports the genome sequence of Auanema rhodensis, a nematode with three sexes, and identifies conserved and rearranged chromosomal units, as well as candidate genes involved in sex determination.

Sensory neurons control heritable adaptation to stress through germline reprogramming

The paper shows that maternal sensory neurons and histone modifications influence offspring sex and stress resistance in nematodes through environmental cues.

Gender- and gamete-specific patterns of X chromosome segregation in a three-gendered nematode

The paper studies X chromosome segregation patterns in a three-gendered nematode, revealing gender- and gamete-specific meiotic variations.