Author

Talal Al‐Yazeedi

Liverpool School of Tropical MedicineORCID 0000-0003-0835-958XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genomics· 2 Ecology· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Research Focus:gene regulatory network inference· 3 Research Focus:variant calling· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

Abdullahi MuhammadiD· 4 shared Charles Sinclair WondjiiD· 3 shared Jack HearniD· 3 shared André Pires‐daSilvaiD· 2 shared Helen Irving· 2 shared Omer S. AlkhnbashiiD· 2 shared Sophie TandonnetiD· 2 shared Ahmed Abou Tayoun· 1 shared

Activity by Year

2022-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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4 shared papersGenomics

Abdullahi MuhammadORCID

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7 papers

Recent·Most cited

GenomicsBMC GenomicsPeer-reviewedOct 31, 2026

The metabolic resistance blueprint: Genomic dissection of DDT resistance in historical kdr-free East African Anopheles gambiae

Talal Al‐Yazeedi, Marion Morris, Abdullahi Muhammad…·Hilary Ranson

This paper identifies genomic loci and mutations associated with DDT metabolic resistance in Anopheles gambiae using bulk segregant analysis and confirms their selection in natural populations.

DOI 10.1186/s12864-026-13466-4

Drosophilawhole-genome sequencing

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EcologyInsect Biochemistry and Molecular BiologyPeer-reviewedAug 15, 2026

Generational selection, transcriptomics and functional characterization reveal the impact of environmental pollutants on the evolution of insecticide resistance in malaria vectors

Abdullahi Muhammad, Sulaiman S. Ibrahim, Helen Irving…·Charles Sinclair Wondji

The paper investigates how environmental pollutants like PAHs affect insecticide resistance in malaria vectors through multi-generational selection experiments and transcriptomic analysis.

DOI 10.1016/j.ibmb.2026.104661

humanbulk RNA-seq

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Genetic & Genomic MedicinemedRxivPreprintJun 18, 2026

Structural variation landscape of Middle Eastern and North African individuals from long-read nanopore sequencing reveals medically relevant variants

Talal Al‐Yazeedi, Sophie Tandonnet, Sven Hauns…·Omer S. Alkhnbashi

The paper identifies structural variants in MENA individuals using long-read sequencing, revealing previously unreported variants and population-specific disease-related variants.

DOI 10.64898/2026.02.20.26346743

humanlong-read sequencing

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GenomicsbioRxivPreprintApr 16, 2025

Genetic mapping of resistance: A QTL and associated polymorphism conferring resistance to alpha-cypermethrin in Anopheles funestus

Talal Al‐Yazeedi, Grâce Djuifo, Leon M. J. Mugenzi…·Charles Sinclair Wondji

This study identifies a QTL and associated polymorphisms conferring resistance to alpha-cypermethrin in Anopheles funestus using genetic crosses and BSA mapping.

DOI 10.1101/2025.04.16.649184

statistical modelgene regulatory network inference

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GeneticsbioRxivPreprintAug 25, 2023

Overexpression and nonsynonymous mutations of UDP-glycosyltransferases potentially associated with pyrethroid resistance in Anopheles funestus

Talal Al‐Yazeedi, Abdullahi Muhammad, Helen Irving…·Charles Sinclair Wondji

The paper identifies overexpression and nonsynonymous mutations in UGT genes associated with pyrethroid resistance in Anopheles funestus using GWAS-PoolSeq and transcriptomic analysis.

1 citation

whole-genome sequencingstatistical model

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Developmental BiologybioRxivPreprintMay 16, 2023

The contribution of an X chromosome QTL to non-Mendelian inheritance and unequal chromosomal segregation in A. freiburgense

Talal Al‐Yazeedi, Sally Adams, Sophie Tandonnet…·André Pires‐daSilva

The paper identifies an X chromosome QTL associated with non-Mendelian inheritance and nullo-spermatid elimination in A. freiburgense.

DOI 10.1101/2023.05.16.540925

Arabidopsisstatistical model

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Developmental BiologyGeneticsPeer-reviewedOct 18, 2022

The X chromosome is a potential polarising signal for asymmetric cell divisions in meiotic cells of a nematode

Talal Al‐Yazeedi, Emily L Xu, Jasmin Kaur…·André Pires‐daSilva

The paper identifies the X chromosome as a polarising signal for asymmetric cell division in nematode meiotic cells, where it directs the segregation of essential sperm components.

5 citations

experimental assay

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