Lauren Ann Metskas

Using Cryogenic Electron Tomography (cryoET) to Determine Rubisco Polymerization Constants in α-Carboxysomes

This paper uses cryoET to determine Rubisco polymerization constants in α-carboxysomes by converting tomography data into binding curves.

Identifying differential effects from eleven mixing techniques on mRNA lipid nanoparticle physicochemistry and biological performance

The paper compares the effects of eleven mixing techniques on mRNA lipid nanoparticle physicochemistry and biological performance, finding significant differences in particle properties and performance across methods.

Systematic Characterization of Optical Aberrations Reveals Cryo-FLM Localization Fidelity

This study systematically analyzes optical aberrations in cryo-FLM, showing they cause localization errors up to 300 nm axially and introduces models to reduce errors to under 10 nm.

A toolkit to characterize protein polymerization from cryo-electron tomography data

The paper introduces a MATLAB script package for unbiased analysis of protein polymerization from cryo-ET data, demonstrating its application to Rubisco in -carboxysomes.

Structure of Anabaena flos-aquae gas vesicles revealed by cryo-ET

This study uses cryo-electron tomography to reveal the structure of Anabaena flos-aquae gas vesicles, showing how GvpA subunits form the shell and how GvpC provides structural reinforcement.

In situ imaging of bacterial membrane projections and associated protein complexes using electron cryo-tomography

The paper uses electron cryo-tomography to analyze membrane projections and associated protein complexes in bacterial species, identifying diverse structures and protein associations.