Takahiro Ochiya

Curability Difference between Autochthonous Mouse Tumors and Their Transplants in Association with Immune Gene Expression

The paper compares immune gene expression in autochthonous mouse tumors and their transplants, finding differences in curability linked to immune markers.

Stress-induced brain extracellular vesicles ameliorate anxiety behaviour.

This study shows that stress-induced brain extracellular vesicles reduce anxiety in mice, and three miRNAs within these vesicles contribute to the anxiolytic effect by suppressing Mecp2 in neurons.

Therapeutic ability of extracellular vesicles derived from angio-miRNA-modified mesenchymal stromal cells in ischemic animal models

This study shows that EVs from angio-miRNA-modified MSCs enhance angiogenesis in ischemic models, with combined EVs showing greater efficacy.

Human bronchial epithelial cell-derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF-β-WNT crosstalk

This paper shows that human bronchial epithelial cell-derived extracellular vesicles reduce pulmonary fibrosis by inhibiting TGF-β-WNT crosstalk through miRNA-mediated mechanisms.