Yu Fujita

From Lab to Industry: Awareness of the translational potential of Extracellular Vesicles by the ISEV Translation, Regulation and Advocacy Committee (ISEV-TRA).

The paper surveys awareness of extracellular vesicles' translational potential across academia and industry, highlighting growing interest and spin-out efforts in EV-based products.

Metabolic Deficiencies Underlie Plasmacytoid Dendritic Cell Exhaustion After Viral Infection

This study identifies LDHB as a key regulator of pDC IFN-I production and metabolic capacity during viral infection, linking metabolic deficiencies to pDC exhaustion and its dual role in immunity and pathology.

Lipogenic Lung Fibroblast-derived Extracellular Vesicles Mitigate Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease Pathologies through LAT1-mediated Alveolar Type II Cell Restoration

This study shows that lipogenic lung fibroblast-derived extracellular vesicles reduce COPD pathologies by restoring alveolar type II cells via LAT1-mediated mechanisms.

Human bronchial epithelial cell-derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF-β-WNT crosstalk

This paper shows that human bronchial epithelial cell-derived extracellular vesicles reduce pulmonary fibrosis by inhibiting TGF-β-WNT crosstalk through miRNA-mediated mechanisms.