Cancer BiologybioRxivPreprint
Novel SLAMF1-derived peptide induces apoptosis in multiple myeloma cells by targeting IRF4 transcription factor for degradation
Ingvild Bergdal Mestvedt, Eline Menu, Kristine Misund…·Maria Yurchenko
This study identifies a SLAMF1-derived peptide, P7N4, that induces apoptosis in multiple myeloma cells by degrading IRF4, enhancing chemotherapy efficacy and showing minimal toxicity to healthy cells.