Terje Espevik

This study shows that cell-intrinsic complement C3 suppresses IFN-β production in macrophages by limiting IRF3-TBK1 complex formation.

This study identifies P7-Pen as a peptide that enhances monocyte inflammatory responses in sepsis by modulating histone acetylation through ABHD14B.

This study identifies a peptide that inhibits TLR7- and TLR8-induced type I IFN responses by disrupting TIRAP-MyD88 interaction, with species-specific effects observed.

This study shows Rab11-FIP2 and Rab11b regulate NLRP3 inflammasome activation in human macrophages by controlling caspase-1 cleavage, pyroptosis, and NLRP3 translocation to the trans-Golgi network.

This study identifies a SLAMF1-derived peptide, P7N4, that induces apoptosis in multiple myeloma cells by degrading IRF4, enhancing chemotherapy efficacy and showing minimal toxicity to healthy cells.

This study identifies Raver1 as a regulator of Ripk1 RNA splicing, which affects caspase-8-mediated pyroptosis, inflammation, and resistance to Yersinia infection.

This study investigates SARS-CoV-2-induced host responses in human lung epithelial cells using multi-omics approaches, revealing altered signaling pathways and metabolic changes.