Cancer BiologybioRxivPreprint
Whole genome CRISPR knockout screen reveals ID3 as a key regulator of myeloma cell survival via TCF3 and c-MYC
Clara Andersson-Rusch, Md. Abu Hanif, Ingrid Quist-Løkken…·Toril Holien
DOI 10.1101/2025.09.09.675036
Author
Norwegian University of Science and TechnologyORCID 0000-0002-8742-7028Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
Recent·Most cited
Clara Andersson-Rusch, Md. Abu Hanif, Ingrid Quist-Løkken…·Toril Holien
Ingvild Bergdal Mestvedt, Eline Menu, Kristine Misund…·Maria Yurchenko
This study identifies a SLAMF1-derived peptide, P7N4, that induces apoptosis in multiple myeloma cells by degrading IRF4, enhancing chemotherapy efficacy and showing minimal toxicity to healthy cells.