Author

Xavier Mialhe

Centre National de la Recherche ScientifiqueORCID 0000-0002-0816-7898Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:multiple species· 1 Approach:statistical model· 1

Frequent Co-Authors

Adeline TorroiD· 1 shared Aline Bajek· 1 shared Aurélie GennetieriD· 1 shared Benjamin GeffroyiD· 1 shared Benoît MiottoiD· 1 shared Camille HoudeletiD· 1 shared Céline GongoraiD· 1 shared Cyril RibeyreiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Adeline TorroORCID

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2 papers

Recent·Most cited

Identifying sexually dimorphic circulating microRNAs in gonochoristic and hermaphroditic marine fish species.

Benjamin Geffroy, Camille Houdelet, Eva Blondeau‐Bidet, Xavier Mialhe, Aline Bajek, Jean‐Claude Falguière, Yann Guiguen, Julien Bobe

The paper identifies sex-specific circulating microRNAs in marine fish species to distinguish males from females and track sexual development stages.

Molecular Reproduction and Development · Jun 1, 2025Peer-reviewedMolecular Biology

Targeting SUV4-20H epigenetic enzymes as therapeutic strategy for enhancing topoisomerase II poisoning in prostate cancer

Fatima Alhourani, Marine Tauziet, Julie Patouillard, Benoît Miotto, Véronique Baldin, Aurélie Gennetier, Simon George, Xavier Mialhe, Cyril Ribeyre, Philippe Pourquier, Florence M. Cammas, Adeline Torro, Diégo Tosi, Céline Gongora, Mona Dergham, , Eric Julien

This study shows that inhibiting SUV4-20H enzymes enhances the effectiveness of TOP2 poisons in prostate cancer by increasing DNA damage and impairing repair mechanisms.

bioRxiv · Mar 11, 2025 · PreprintCancer Biology