Yann Guiguen

The paper studies gene regulatory evolution in salmonids after autotetraploidization, finding that it is influenced by developmental and tissue-specific factors, with constraints at advanced embryogenesis.

The paper identifies sex-specific circulating microRNAs in marine fish species to distinguish males from females and track sexual development stages.

The paper investigates QTL regions associated with spontaneous sex-reversal in XX rainbow trout using genome-based approaches and statistical methods to identify potential sex-modifier genes.

The paper presents chromosome-level genome assemblies for three hybridizing Cobitis species to study hybrid sterility and asexuality, revealing structural variation and sex chromosome divergence.

The paper examines gene expression variability across organs in three ray-finned fish species, finding that brain-biased genes show stable regulation despite inter-individual differences.

The paper assembles and characterizes the ZW sex chromosomes in M. macrocephalus using PacBio and Hi-C, identifying candidate genes for sex determination.

The paper compares genomes across multiple fish species to study the evolutionary changes in the amhr2bY gene, a key sex-determining gene, revealing gains and losses in different Percidae species.

The paper constructs a high-resolution comparative atlas of paleopolyploid regions across 74 teleost genomes to study rediploidization and finds that some duplicated regions remained tetraploid for over 60 million years.

The paper identifies a truncated duplication of the amhr2 gene on the Y chromosome in Pangasiid catfishes as a conserved master sex-determining gene.

The study identifies a non-functional sdY gene variant in XY Chinook salmon females that disrupts testicular differentiation by impairing estrogen synthesis.

RADSex is a computational workflow for analyzing RAD-Seq data to identify sex determination systems, uncovering new sex-specific markers in fish species.

The paper investigates the genetic basis of spontaneous masculinization in XX female rainbow trout using GWAS and WGS, identifying candidate genes associated with maleness.

This study characterizes the sex determination system and sex chromosomes in goldfish, identifying a large non-recombining region on linkage group 22 as the likely Y chromosome and developing sex-linked genetic markers.

SCORPiOs improves gene phylogenies in teleost fish by integrating syntenic information, resolving inconsistencies in 70% of gene families and enhancing congruence with species trees and expression patterns.

The paper presents a high-quality draft genome assembly of Oryzias javanicus, focusing on its adaptation to salinity.

The paper presents a chromosome-scale genome assembly of yellow perch and identifies a Y-specific duplication of the amhr2 gene as a candidate sex determination gene.

The paper identifies RUNX1 as a conserved regulator of fetal ovarian supporting cell identity, showing its interaction with FOXL2 in maintaining granulosa cell fate across species.

The foxr1 gene in zebrafish is a novel maternal-effect gene required for proper cell division in early embryonic development through regulation of p21 and rictor.

The paper introduces FAASG, an initiative to study salmonid genomes to understand phenotypic variation and improve aquaculture and conservation.