Author

Elena O. Gracheva

Yale UniversityORCID 0000-0002-0846-3427Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:multiple species· 2 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Luke H. ZiolkowskiiD· 3 shared Sviatoslav N. BagriantseviD· 3 shared C. Shan XuiD· 2 shared Song PangiD· 2 shared Viktor V. FeketaiD· 2 shared Yury A. NikolaeviD· 2 shared A Chikamoto· 1 shared Bruno GegenhuberiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Luke H. ZiolkowskiORCID

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Author profile →

4 papers

Recent·Most cited

The functional diversification of somatosensory neuron repertoires across Mammalia

S. Andrew Shuster, Jia Yin Xiao, Bruno Gegenhuber, Shamsuddin A. Bhuiyan, Min Dai, Yongting Chen, Michelle M. DeLisle, Preston Sheng, Elizabeth Howell, Michael Brecht, Elena O. Gracheva, Cynthia F. Moss, David L. Paul, Ishmail Abdus-Saboor, Gord Fishell, , David D. Ginty

The paper shows that somatosensory neuron repertoires in mammals diversify through changes to conserved neuron types, enabling adaptation to different habitats and body forms.

bioRxiv · Sep 21, 2026 · PreprintNeuroscience

Structural and functional dissection of the Pacinian corpuscle reveals an active role of the inner core in touch detection

Luke H. Ziolkowski, Yury A. Nikolaev, A Chikamoto, Mai Oda, Viktor V. Feketa, David Monedero Alonso, Serafima A. Ardasheva, Samuel S. Bae, C. Shan Xu, Song Pang, Elena O. Gracheva, Sviatoslav N. Bagriantsev

This study reveals that the inner core of Pacinian corpuscles, not the outer core, mediates rapid adaptation and frequency tuning in touch detection.

Science Advances · Feb 26, 2025Peer-reviewedNeuroscience

3D architecture and a bi-cellular mechanism of touch detection in mechanosensory corpuscle

Yury A. Nikolaev, Luke H. Ziolkowski, Song Pang, Weiping Li, Viktor V. Feketa, C. Shan Xu, Elena O. Gracheva, Sviatoslav N. Bagriantsev

This study reveals the 3D architecture of avian Meissner corpuscles and identifies a bi-cellular mechanism where lamellar cells release neurotransmitters to trigger action potentials in afferents for touch detection.

Science Advances · Sep 13, 2023Peer-reviewedNeuroscience

Mechanotransduction events at the physiological site of touch detection

Luke H. Ziolkowski, Elena O. Gracheva, Sviatoslav N. Bagriantsev

The paper uses patch-clamp recordings to study mechanotransduction in duck Meissner corpuscle afferents, showing fast kinetics of mechanically activated current and rapidly adapting firing.

eLife · Jan 6, 2023Peer-reviewedNeuroscience