Author

Débora Serrenho

Centro de Neurociências e Biologia CelularORCID 0000-0002-0982-8336Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

Ana Luı́sa CarvalhoiD· 2 shared Alexandra SilvaiD· 1 shared Andreia Neves‐CarvalhoiD· 1 shared Andreia Teixeira‐CastroiD· 1 shared Ângela S. InácioiD· 1 shared Annalisa PastoreiD· 1 shared Beatriz Rocha Ilidio RodriguesiD· 1 shared Carter LantziD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Ana Luı́sa CarvalhoORCID

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2 papers

Recent·Most cited

NeuroscienceCommunications BiologyPeer-reviewedMar 20, 2026

Neuronal ARHGAP8 controls synapse structure and AMPA receptor-mediated synaptic transmission

Jeannette Schmidt, Ângela S. Inácio, Joana S. Ferreira…·Ana Luı́sa Carvalho

This study identifies ARHGAP8 as a novel synaptic protein involved in excitatory synapse morphology and function, with implications for neurodevelopmental and psychiatric disorders.

1 citation

mouseelectronic health records

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BiophysicsAdvanced SciencePeer-reviewedNov 26, 2025

Allosteric Modulation of Pathological Ataxin-3 Aggregation: A Path to Spinocerebellar Ataxia Type-3 Therapies

Alexandra Silva, Sara Duarte‐Silva, Pedro Miguel Martins…·Sandra Macedo‐Ribeiro

This study shows that CLR01, a supramolecular tweezer, reduces Atx3 aggregation by binding to a specific site, delaying fibril formation and improving symptoms in SCA3 models.

DOI 10.1002/advs.202502216

humanC. elegans

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