Arren Bar‐Even

This paper presents a computational workflow for designing and testing E. coli metabolic sensors that detect glyoxylate and glycolate across a wide concentration range, with applications in bioengineering and environmental monitoring.

This study replaces the glycerate pathway with the β-hydroxyaspartate cycle in Pseudomonas putida, resulting in faster growth and higher biomass yield on ethylene glycol.

The paper engineers a synthetic one-carbon fixation pathway in Cupriavidus necator that achieves higher biomass yield than the native Calvin Cycle.

The paper engineers a synthetic C1-assimilation cycle in E. coli to enable growth on formate, demonstrating the feasibility of synthetic carbon fixation from CO2.

This paper optimizes an E. coli strain for formate-based bioproduction using the reductive glycine pathway, achieving improved growth and lactate production.

The paper studies the flexibility of the amination network in E. coli by identifying key enzymes and amino acids involved in ammonium assimilation and glutamate production.

This study identifies alternative glycolytic pathways in E. coli that bypass canonical EMP glycolysis, showing that the serine shunt is selected for in adaptive evolution.

This study identifies a new carbon fixation pathway in E. coli using only native enzymes and demonstrates its in vivo feasibility through genetic engineering.

The paper demonstrates that a bacterial CO2 concentrating mechanism enables E. coli to fix CO2 from ambient air using 20 CCM genes.

This study replaces the Calvin cycle in Cupriavidus necator with a synthetic reductive glycine pathway to improve formate assimilation and growth.