Author

Andréa Cottignies-Calamarte

Centre National de la Recherche ScientifiqueORCID 0000-0002-1041-4659Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

Alejandro De CruziD· 1 shared Amelie WileveauiD· 1 shared Benoît ViolletiD· 1 shared Cyril PlanchaisiD· 1 shared Daniela TudoriD· 1 shared Eva Thuillier· 1 shared Feifan He· 1 shared Felix Augusto ReyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Alejandro De CruzORCID

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2 papers

Recent·Most cited

TMPRSS2 reduces antibody recognition of SARS-CoV-2 spike

Andréa Cottignies-Calamarte, Alejandro De Cruz, Cyril Planchais, Françoise Porrot, Mateo Kryzpow, Martin Jungbauer-Groznica, Eva Thuillier, Amelie Wileveau, Isabelle Staropoli, Florence Guivel‐Benhassine, Pierre Rosenbaum, I. Fernández, Felix Augusto Rey, Julian Buchrieser, Sophie Trouillet‐Assant, , Timothée Bruel

This study shows TMPRSS2 reduces antibody binding to SARS-CoV-2 spike by altering its structure and shedding, but not virion infectivity.

bioRxiv · Feb 25, 2026 · PreprintImmunology

Direct pharmacological AMPK activation inhibits mucosal SARS-CoV-2 infection by reducing lipid metabolism, restoring autophagy flux and the type I IFN response

Andréa Cottignies-Calamarte, Flora Marteau, Feifan He, Sandrine Belouzard, Jean Dubuisson, Daniela Tudor, Benoît Viollet, Morgane Bomsel

This paper shows that MK-8722, a direct AMPK activator, inhibits SARS-CoV-2 infection by reducing lipid metabolism, restoring autophagy, and enhancing type I IFN response, even when applied post-exposure.

Journal of Virology · Jun 12, 2025Peer-reviewedImmunology