Julian Buchrieser

This study shows human coronavirus HKU1 replicates more efficiently at nasal temperature (33°C) than at body temperature (37°C), with differences in innate immune response and viral stability.

This study shows TMPRSS2 reduces antibody binding to SARS-CoV-2 spike by altering its structure and shedding, but not virion infectivity.

This study investigates how HIV forms CPSF6 puncta and their fusion with nuclear speckles, identifying key domains and factors involved in this process and its role in viral persistence.

This study shows that SARS-CoV-2 entry and fusion depend on cholesterol but not on ACE2 localization to lipid rafts.

This study determines the structure of HKU1-CoV receptor binding domain in complex with TMPRSS2, identifying key residues for host tropism and revealing the structural basis of TMPRSS2 activation.

The paper shows that extracellular vesicles with ACE2 can block SARS-CoV-2 infection more effectively than soluble ACE2.