Adrián Plaza-Pegueroles

This study uses cryo-EM to reveal a two-step mechanism of RNA polymerase I stalling at abasic DNA lesions, distinct from other lesion types.

This study presents the cryo-EM structure of trypanosome 3-methylcrotonyl-CoA carboxylase, revealing its mechanism and dynamic features relevant to drug discovery.

This study determines the structural basis of Ty1 integrase interaction with RNA polymerase III, revealing key residues and conformational changes that facilitate targeted DNA integration.