Ruslan Aphasizhev

The cryo-EM structure of trypanosome 3-methylcrotonyl-CoAcarboxylase provides mechanistic and dynamic insights into enzymatic function

This study presents the cryo-EM structure of trypanosome 3-methylcrotonyl-CoA carboxylase, revealing its mechanism and dynamic features relevant to drug discovery.

Discovery, Structure, and Function of Filamentous 3-Methylcrotonyl-CoA Carboxylase

This study discovers that native MCC from Leishmania tarentolae forms filaments, determines its structure, and proposes a new model for its catalytic mechanism.

A toolkit to handle T-less alignment for U insertion/deletion RNA editing

The paper introduces a toolkit for aligning and analyzing U insertion/deletion RNA editing data from kinetoplastid mitochondrial genomes.