Author

Nora S. Siefert

German Cancer Research CenterORCID 0000-0002-1101-2264Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Wilhelm PalmiD· 2 shared Alexander KowariD· 1 shared Ali Hyder Baig· 1 shared Anastasija PanevaiD· 1 shared Andrea ZanottiiD· 1 shared Beiping MiaoiD· 1 shared Catarina PechinchaiD· 1 shared Chong SuniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Wilhelm PalmORCID

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2 papers

Recent·Most cited

Mammalian RAVE couples V-ATPase assembly to organelle acidification and function

Nora S. Siefert, Andrea Zanotti, Anastasija Paneva, Martin Schneider, Dominic Helm, Wilhelm Palm

This study identifies mRAVE as a mammalian V-ATPase assembly factor that links organelle acidification to function and nutrient signaling.

bioRxiv · Dec 11, 2025 · PreprintCell Biology

Dual Ribosome Profiling reveals metabolic limitations of cancer and stromal cells in thetumor microenvironment

Daniela Avilés Huerta, Rossella Del Pizzo, Alexander Kowar, Ali Hyder Baig, Giuliana Palazzo, Ekaterina Stepanova, Cinthia Claudia Amaya Ramirez, Sara D’Agostino, Edoardo Ratto, Catarina Pechincha, Nora S. Siefert, Helena Engel, Shangce Du, Silvia Cadenas-De Miguel, Beiping Miao, , Fabricio Loayza‐Puch

This study uses Dual Ribosome Profiling to reveal cell type-specific metabolic limitations in the tumor microenvironment, showing how amino acid availability affects immunotherapy outcomes.

Nature Communications · May 19, 2025Peer-reviewedCancer Biology