Cell BiologybioRxivPreprint
Cyclin D-CDK4/6 couple proliferation to membrane and mitochondrial protein supply through a DeSI1 phospho-switch
Sharon Kaisari, Ethan Lane, Raymond Wang…·Michele Pagano
This study identifies DeSI1 as a cyclin D-CDK4/6 substrate whose phosphorylation regulates membrane and mitochondrial protein supply during proliferation.
DOI 10.64898/2026.09.16.752001