Marija Drikic

This study identifies microbiome-derived hydroxyphenyl propanoates (HPPs) that enhance antitumour immunity by boosting gasdermin D activity in myeloid cells, improving immune checkpoint therapy outcomes in mice and correlating with better responses in human melanoma patients.

This study shows that fumarate, regulated by host and pathogen, limits S. aureus growth by blocking metabolic pathways, while FumC enables adaptation through fumarate degradation and utilization.