Author

Renuka R. Nayak

University of California, San FranciscoORCID 0000-0002-1123-4668Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Organism:human· 3 Assay:metagenomics· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

Peter James TurnbaughiD· 3 shared Diego A. OrellanaiD· 2 shared José U. ScheriD· 2 shared Rebecca B. BlankiD· 2 shared Alexandra L. DegraeveiD· 1 shared Andrew D. PattersoniD· 1 shared Annamarie E. BustioniD· 1 shared Ayushi AgrawaliD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMicrobiology

Peter James TurnbaughORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintMar 30, 2026

Multi-cohort Analysis Reveals Microbiome Signatures Associated with Drug Response in New-Onset Rheumatoid Arthritis

Rahul Bodkhe, Rebecca B. Blank, Kai R. Trepka…·Renuka R. Nayak

The paper analyzes microbiome data from multiple cohorts to identify consistent signatures associated with methotrexate response in rheumatoid arthritis patients.

DOI 10.64898/2026.03.30.715090

humanmetagenomics

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Pharmacology & ToxicologybioRxivPreprintJun 26, 2025

The gut microbiome shapes pharmacology and treatment outcomes for a key anti-inflammatory therapy

Vanya Sofia Villa Soto, Alexandra L. Degraeve, Chloe M. Heath…·Renuka R. Nayak

This study shows that the gut microbiome affects methotrexate pharmacology in mice and contributes to interindividual variation in drug metabolism and treatment outcomes.

4 citations

mousehuman

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BioinformaticseLifePeer-reviewedJun 12, 2023

A novel in silico method employs chemical and protein similarity algorithms to accurately identify chemical transformations in the human gut microbiome

Annamarie E. Bustion, Renuka R. Nayak, Ayushi Agrawal…·Katherine S. Pollard

25 citations

humanmetagenomics

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