Sándor Nietzsche

Synergistic cross-kingdom host cell damage between Candida albicans and Enterococcus faecalis

This study shows that Candida albicans and Enterococcus faecalis synergistically increase host cell damage through physical interaction and glucose depletion.

A plug-and-play transepithelial/transendothelial electric resistance (TEER)-upgraded organ-on-chip system to measure barrier dynamics in real-time

This paper introduces a plug-and-play TEER system integrated into an organ-on-chip platform for real-time barrier dynamics monitoring, showing improved sensitivity over conventional methods.

The murine lung microbiome is dysbalanced by the human pathogenic fungus Aspergillus fumigatus resulting in enrichment of anaerobic bacteria

This study shows that Aspergillus fumigatus infection in immunosuppressed mice disrupts lung microbiome balance, increasing anaerobic bacteria like Ligilactobacillus murinus, which can be internalized by epithelial cells.

Galleria mellonella model for studying Gram-positive bacterial implant biofilms

This study evaluates the Galleria mellonella model for assessing biofilm formation by S. aureus and E. faecalis on implant materials, showing its effectiveness in mimicking clinical infections and antibiotic responses.

Telomerase RNA component knockout exacerbates S. aureus pneumonia by extensive inflammation and dysfunction of T cells

This study shows that Terc knockout mice are more susceptible to S. aureus pneumonia due to increased inflammation and impaired T cell function.